Pharmacogenetics

Certified and accredited to highest quality standards. Laboratory services delivering safe and reliable results for personalized medicine including drug response and metabolism.

Premium laboratory services for Pharmacogenetics 
for genotype-guided therapy.

Path to Pharmacogenetics

Cytochrome P450 (CYP) enzymes are a group of enzymes commonly involved in drug metabolism, and genetic variation in the genes encoding CYPs are associated with variable drug response. The genes CYP2D6CYP2C9CYP2C19, and CYP3A4 are the most functionally important in Pharmacogenomics [1].

Additionally with Rare Diseases, CYP2D6 plays an an essential role in therapies such as substrate reduction therapy [2].

Find a comprehensive list of Pharmacogenomic Genes and Associated Drugs here (external link).

CYP2D6 Genotyping

Fully validated and accredited CYP2D6 genotyping identifying over 15 polymorphism variants including gene rearrangements associated with the deletion (*5) and duplication genotypes. Available fast and easy from Dried Blood Spots.

Additional genetic testing options:

Gene OMIM # Inheritance
CYP1A1 108330 Mult and / or SMu
CYP1A2 124060 AR
CYP2C19 124020 AR
CYP2C9 601130 AD
CYP2C6 124030 AR

Quality:

Fully validated and accredited according to the highest quality standards for Medical Laboratories (ISO 15189).

Methodologies used:

  • Genetics by CYP2D6 polymorphism identification.
  • Genetics by Next-Generation Sequencing platforms.

About Pharmacogenetics

What is Pharmacogenetics?

Pharmacogenetics (PGx) is the science of understanding how genetic variability influences drug treatment outcomes.

Why is it so important?

Pharmacogenetic studies allow us to better understand the pharmacology of medications. This influences both the pharmacokinetics and pharmacodynamics of medications relevant for dosing, therapeutic sensitivity, likelihood of side-effects, and risk for hypersensitivity reactions [3].

What is the difference between pharmacogenetics and pharmacogenomics?

Pharmacogenetics usually refers to how a variation in a single gene influences the response to a single drug. In contrast, Pharmacogenomics is a broader term, which studies how all of the genes (the genome) can influence an individual’s response to drugs or drug therapies.

How to Order Pharmacogenetic Laboratory Services

ARCHIMEDlife Sampling Kit

We support Pharmacogenetic testing with fully valildated and accredited assays. We offer fast and reliable testing for CYP2D6 plus other important Cytochrome P450 genes using Dried Blood Spots.

These services are available to any interested physician or healthcare professional worldwide.

As part of our service, we supply complimentary ARCHIMEDlife sampling kits. You can order your sampling kits and services though our easy and secure WEBPORTAL and receive your eletronic medical report in five simple steps.

Five Simple Steps


1Order Sampling Kit

2Collect the Sample

3Register the DBS card

4Return the Sample

5Receive your Report

More questions about Pharmacogenetics
and supporting diagnostics?

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